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what is lentigo maligna melanoma

Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are types of skin cancer. They begin when the melanocytes in the skin grow out of control and form tumors. Melanocytes are the cells responsible for making melanin, the pigment that determines the color of the skin.

How fast does lentigo maligna melanoma spread?

It grows slowly in diameter over 5 to 20 years or longer. Lentigo maligna melanoma is diagnosed when the melanoma cells have invaded into the dermis and deeper layers of skin. Lentigo maligna has a lower rate of transformation to invasive melanoma than the other forms of melanoma in situ (under 5% overall).

What is the prognosis of lentigo maligna melanoma?

Patients with stage IV melanoma generally have a poor prognosis. From the time the metastasis is diagnosed, the median survival is 6-7.5 months, with a 5-year survival rate of approximately 6%. Patients with neck and scalp melanoma have shorter survival compared with melanoma at other sites (extremities, face, trunk).

Is lentigo maligna curable?

Diagnosis and Treatment of Lentigo Maligna Melanoma LM and LMM are highly curable when diagnosed early.

Is lentigo maligna invasive?

Lentigo maligna melanoma is a type of invasive skin cancer. It develops from lentigo maligna, which is sometimes called Hutchinson's melanotic freckle. Lentigo maligna stays on the outer surface of the skin.

How serious is lentigo maligna melanoma?

Lentigo maligna is not dangerous; it only becomes potentially life threatening if an invasive melanoma develops within it. Long term follow-up involves reviewing the treated area and full skin examination to identify new lesions of concern. If the lesion was invasive, regional lymph nodes should also be examined.

What does lentigo melanoma look like?

The visual symptoms of lentigo maligna melanoma are very similar to those of lentigo maligna. Both look like a flat or slightly raised brown patch, similar to a freckle or age spot. They have a smooth surface and an irregular shape. While they're usually a shade of brown, they can also be pink, red, or white.

Is lentigo maligna cancerous?

Lentigo maligna is the precursor to a subtype of melanoma called lentigo maligna melanoma, which is a cancerous (malignant) growth of the cells that give our skin cells color.

What is the difference between lentigo maligna and melanoma in situ?

Lentigo maligna may appear as a long- standing discoloured patch of skin, most commonly on the face, which slowly enlarges and develops darker areas with in it. Most in situ melanomas do not cause any symptoms, but tingling or itching may occur.

Does lentigo maligna melanoma spread?

Lentigo maligna grows slowly and is usually harmless, but lentigo maligna melanoma can spread aggressively. It's important to recognize the symptoms of lentigo maligna melanoma so you can seek treatment early on.

What does lentigo maligna look like?

What does lentigo maligna look like? Lentigo maligna commonly looks like a freckle, age spot, sun spot or brown patch that slowly changes shape and grows in size. The spot may be large in size, irregularly shaped with a smooth surface, and of multiple shades of brown and sometimes other colours.

What triggers melanoma?

The exact cause of all melanomas isn't clear, but exposure to ultraviolet (UV) radiation from sunlight or tanning lamps and beds increases your risk of developing melanoma.

What causes lentigo maligna melanoma?

The exact cause of lentigo maligna melanoma is unknown, but sun exposure is the biggest risk factor for developing it. That puts people with sun-damaged skin and those who spend a lot of time outside at a higher risk. Other risk factors for developing lentigo maligna melanoma include: fair or light skin.

Can lentigo maligna disappear?


How is lentigo maligna treated?

Lentigo maligna is treated with surgery. The standard and preferred treatment is surgical excision. However, various nonsurgical modalities are available to patients in whom surgical therapy is not feasible, including cryotherapy and immune response therapy with topical imiquimod.

Is lentigo curable?

Lentigo maligna can be cured with surgery. However, if the whole area is not removed completely with the appropriate surgery, some may develop into an invasive melanoma. It is therefore important to have it removed with a rim of normal skin (an adequate surgical margin).

Is lentigo maligna curable?

Diagnosis and Treatment of Lentigo Maligna Melanoma LM and LMM are highly curable when diagnosed early.

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